trans-4-hydroxy-L-proline amide - Names and Identifiers
Name | 2-Pyrrolidinecarboxamide,4-hydroxy-,(2S,4R)-(9CI)
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Synonyms | Trans-hyp-nh2 Vildagliptin Impurity 49 Vildagliptin Impurity 59 Vildagliptin Impurity 70 trans-4-hydroxy-L-proline amide TRANS-4-HYDROXY-L-PROLINE AMIDE (2S,4R)-4-Hydroxypyrrolidine-2-carboxamide 2-Pyrrolidinecarboxamide, 4-hydroxy-, (2S,4R)- 2-Pyrrolidinecarboxamide,4-hydroxy-,(2S,4R)-(9CI)
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CAS | 61703-38-6
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trans-4-hydroxy-L-proline amide - Physico-chemical Properties
Molecular Formula | C5H10N2O2
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Molar Mass | 130.15 |
Density | 1.299±0.06 g/cm3(Predicted) |
Boling Point | 410.1±45.0 °C(Predicted) |
pKa | 14.50±0.40(Predicted) |
Storage Condition | 2-8℃ |
trans-4-hydroxy-L-proline amide - Introduction
2-Pyrrolidinecarboxamide,4-hydroxy-,(2S,4R)-(9CI), also known as (2-Pyrrolidinecarboxamide,4-hydroxy-,(2S,4R)-(9CI)), it is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
2-Pyrrolidinecarboxamide,4-hydroxy-,(2S,4R)-(9CI) is a colorless to yellowish solid. It can be dissolved in water and some organic solvents at room temperature. Its chemical formula is C9H19NO3 and its molecular weight is 189.25g/mol.
Use:
2-Pyrrolidinecarboxamide,4-hydroxy-,(2S,4R)-(9CI) are widely used as intermediates in chemical synthesis. It is often used in the organic synthesis of catalyst and reaction solvent and so on. In addition, it is also commonly used in the field of medicine, for the preparation of pharmaceutical ingredients and the like.
Method:
2-Pyrrolidinecarboxamide,4-hydroxy-,(2S,4R)-(9CI) can be synthesized by a variety of methods. One common method is to react diethylene glycol with 2-aminoethanol to form the compound. Specific reaction conditions and operating methods can be adjusted according to actual needs.
Safety Information:
under normal use conditions, 2-pyro-lidinecarboxamide,4-hydroxy-,(2S,4R)-(9CI) is generally considered to be a relatively safe compound, but preventive measures are still needed. Wear appropriate personal protective equipment such as chemical gloves, goggles, and lab coats during operation. Avoid contact with skin, eyes and respiratory tract. In case of accidental contact, rinse immediately with plenty of water. At the same time, to maintain good ventilation conditions. In addition, the storage and handling of the compound should follow local safety regulations. If you have any safety concerns, you should consult a chemical expert or the relevant safety agency for advice.
Last Update:2024-04-09 21:11:58